In this talk from the 2022 Advancing Excellence in Transgender Health Care Conference, Dr. Rebekah Viloria discusses reproductive care and obstetrics for Trans and Gender-Diverse people. By the end of this talk, you will be able to acknowledge barriers and challenges to reproductive and sexual health care for LGBTQIA+ persons, incorporate practices to promote an inclusive and affirming clinical environment, understand the impact of gender affirming therapy on reproductive health, and effectively guide LGBTQIA+ persons on family-building options.